Sensitivity of bacterial coaggregation to chelating agents

Design of therapeutic chelating agents.

The successful design of orally active non-toxic selective metal chelators is a much sought-after goal. In order to identify an ideal chelator for clinical use, a range of specifications must be considered, such as metal selectivity and affinity, kinetic stability of the complex, bioavailability and toxicity. In this overview the comparative properties of ligands capable of endowing complexes w...

Chelating agents in biological systems.

Chelation enables metals to be transported to or from vulnerable target sites, and to hinder or facilitate their carcinogenic potential. In the reverse sense, metals are capable of ligand scavenging via complexation or mixed complex formation--the latter being the result of interaction with binary complexes. Consequently, metal complexes can be utilized for the transport of selected organic che...

The Transfer of Iron to Reticulocytes by Synthetic Chelating Agents.

Analyzing Bacterial Agents of Keratoconjunctivitis in Patients Referred to Ophthalmology Ward of Feiz Hospital in Isfahan

Background & Objectives: Keratoconjunctivitis is considered as the most prevalent ocular disease which is caused by multiple microorganisms. Considering the fact that identifying etiologic agents of Keratoconjunctivitis in a specific geographical area, and determining their antibiotic resistance pattern could be very important in specifying treatment strategy of such patients, the present resea...

Iron chelating agents for treating malaria.

BACKGROUND Researchers are exploring the effects of adding treatments to the main antimalarial regimens in an attempt to reduce mortality from Plasmodium falciparum. Iron chelation is one potential chemotherapeutic adjuvant treatment. Before advocating adjunctive therapy, the effects of iron chelators in improving patient outcomes need to be examined. OBJECTIVES To assess the effects of iron-...